Sulfur ylide-initiated thio-claisen rearrangements. The synthesis of highly substituted indolines.
نویسندگان
چکیده
The coupling of rhodium carbenoids from vinyl diazoacetates with 2-thio-3-alkyl indoles was found to generate C(3) quaternary substituted indolines via a thionium ylide-initiated [3,3]-sigmatropic rearrangement.
منابع مشابه
The diastereoselective synthesis of quaternary substituted thioindolines from sulfur ylide intermediates.
The Rh(II)-catalyzed coupling of chiral 2-thiopyranylindoles with vinyl diazoacetates results in the generation of indolines having quaternary substitution at C3 in high diastereoselectivity.
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عنوان ژورنال:
- The Journal of organic chemistry
دوره 68 3 شماره
صفحات -
تاریخ انتشار 2003